Methicillin, Vancomycin, Teicoplanin and Macrolide-Lincosamide-Streptogramin B (MLSB) Resistance in Staphylococcus aureus Isolated from Postmortem Samples

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Prevalence of Macrolide-Lincosamide-Streptogramin B (MLSB) Resistance in S. aureus Isolated from Patients in Tehran, Iran

Background and Objectives: Staphylococcus aureus is an important cause of nosocomial and community-acquired infections in every region of the world. Clindamycin is one of the alternative agents used to treat S. aureus infections and accurate identification of clindamycin resistance is important to prevent therapeutic failure. Unfortunately, inducible clindamycin resistance is ...

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Prevalence of Macrolide-Lincosamide-Streptogramin B (MLSB) Resistance in Staphybcoccus aureus Isolated from Patients in Tehran, Iran

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Constitutive and Inducible Clindamycin Resistance Frequencies among Staphylococcus sp. Coagulase Negative Isolates in Al-Basrah Governorate, Iraq

Background: Antibiotics called macrolide, lincosamide and streptogramin B (MLSB) are being used to treat staphylococci infections. Multiple pathways that impart resistance to MLSB antibiotics have been confirmed to cause clinical failure. The present work aimed to determine the frequency of constitutive and inducible clindamycin resistant among coagulase-negative staphylococci (CoNS) isolates o...

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prevalence of macrolide-lincosamide-streptogramin b (mlsb) resistance in s. aureus isolated from patients in tehran, iran

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Novel locus required for expression of high-level macrolide-lincosamide-streptogramin B resistance in Staphylococcus aureus.

The yycF1(Ts) mutation in Staphylococcus aureus conferred hypersensitivity to macrolide-lincosamide-streptogramin B (MLS(B)) antibiotics on strains either containing or lacking ermB. The overexpression of the S. aureus Ssa protein restored the yycF1 mutant to wild-type levels of susceptibility. Inactivation of ssa in an unmutagenized strain dramatically reduced ermB-based resistance. Conditiona...

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ژورنال

عنوان ژورنال: Ankem Dergisi

سال: 2015

ISSN: 1301-3114

DOI: 10.5222/ankem.2015.001